Functional deficits in carpal tunnel syndrome reflect reorganization of primary somatosensory cortex

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Functional deficits in carpal tunnel syndrome reflect reorganization of primary somatosensory cortex.

Carpal tunnel syndrome, a median nerve entrapment neuropathy, is characterized by sensorimotor deficits. Recent reports have shown that this syndrome is also characterized by functional and structural neuroplasticity in the primary somatosensory cortex of the brain. However, the linkage between this neuroplasticity and the functional deficits in carpal tunnel syndrome is unknown. Sixty-three su...

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Functional deficits in carpal tunnel syndrome.

BACKGROUND Carpal tunnel syndrome (CTS) is a major occupational illness in the US. The Wisconsin Test is a quantitative computer-controlled test battery designed for measuring sensory and psychomotor function. Subjects were recruited from industrial jobs at high-risk for CTS to determine if subtle sensory and motor deficits were observable in a working population. Outcomes were studied for pote...

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Rewiring the primary somatosensory cortex in carpal tunnel syndrome with acupuncture.

Carpal tunnel syndrome is the most common entrapment neuropathy, affecting the median nerve at the wrist. Acupuncture is a minimally-invasive and conservative therapeutic option, and while rooted in a complex practice ritual, acupuncture overlaps significantly with many conventional peripherally-focused neuromodulatory therapies. However, the neurophysiological mechanisms by which acupuncture i...

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Acupuncture Evoked Response in Contralateral Somatosensory Cortex Reflects Peripheral Nerve Pathology of Carpal Tunnel Syndrome.

BACKGROUND Most neuroimaging studies exploring brain response to different acupoints have been performed in healthy adults. OBJECTIVE The aim of this study was to compare brain responses to acupuncture at local versus distal acupoints in patients with carpal tunnel syndrome (CTS), who have chronic pain, versus healthy controls (HC) and correlate these responses with median nerve function. M...

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ژورنال

عنوان ژورنال: Brain

سال: 2014

ISSN: 1460-2156,0006-8950

DOI: 10.1093/brain/awu096